Nā Pōmaikaʻi o Niacin

by Cathy Wong, ND; ʻIkeʻia e Richard N. Fogoros, MD

Ka mea e pono ai eʻike

ʻO Niacin kahi hua hua B i loaʻa i loko o kekahi mau meaʻai a kūʻaiʻia ma keʻano kikowaena. I kekahi manawa i kapaʻiaʻo ka huaʻaina B3, hanaʻia ka lolouma e ke kino.

Hoʻomaopopoʻia e pāʻani i ke kuleana nui i ka hoʻololiʻana i ka meaʻai i ka ikehu, ua manaʻoʻia ka mea nui i kaʻoihana o ka'ōnaehana'ōpiopio, kaʻili, a me nā aʻalolo. ʻOiaiʻo ka maʻiʻole kahi nui loa, ua hoʻohana kekahi poʻe i nā mea hana paʻakai e kōkua ai i kekahi mauʻano olakino.

Hoʻohana

I kekahi lāʻau lapaʻau'ē aʻe, hoʻopuka pinepineʻia nā mea āpau o ka niacin ma keʻano he lapaʻau kūpono no nā pilikia o kēia olakino:

ʻene
ʻO ka maʻi o Alzheimer
maʻi
ka nui o ke koko
nā palapala
maʻi diabet
ke kiʻekiʻe cholesterol
ka migraines
ka maʻi
nā pilikia loli
ka maʻi mua premenstrual

Hoʻopiliʻia, hoʻohanaʻiaʻo niacin e ho'ēmi i nā hopena o kaʻelemakule , e hoʻohaʻahaʻa i ka pilikia, e hoʻonui i ka'ōhumuʻana, a hoʻonā i ka holo.

Nā pōmaikaʻi

Eia ke nānā i kaʻikeʻepekema ma hope o nā hoʻopōmaikaʻi ola o niacin:

1) Ka Cholesterol kiʻekiʻe

ʻO ka laweʻana i ka waiuma he mea pono ia e hoʻohaʻahaʻa i ka cholesterol, e like me nā National Institute of Health (NIH). ʻO kaʻoiaʻiʻo, ua'āponoʻia kekahi mau mea'aʻalacin e ka US Food and Drug Administration e like me nā kauka no ka cholesterol kiʻekiʻe.

Ua hōʻikeʻia kekahi mau ho'āʻo hoʻokolohua e hiki i ka lolo ke kōkua i ka hoʻonui i ke kiʻekiʻe o HDL ("maikaʻi") cholesterol a e ho'ēmi i ke kiʻekiʻe o ka LDL ("hewa") cholesterol. Eia naʻe, i loko o kahi noiʻi hou mai ka New England Journal of Medicine, uaʻike nā kānaka noiʻi heʻoi aku ka maikaʻiʻole o ka maʻi no ka poʻe maʻi me ka maʻi maʻi o ka lolo aku i ka statin therapy.

I ka makahiki 2011, ua kauʻia i loko o ka makahiki 2008, he 3,414 mau kānaka me ka maʻi maʻi maʻi a me ka maʻi atherosclerosis.

Ināʻoe e noʻonoʻo ana i ka hoʻohanaʻiaʻana o ka niacin i ka mālamaʻana i ka cholesterol kiʻekiʻe, e kamaʻilio me kāu kauka ma mua o kou hoʻomakaʻana i kāu polokalamu hoʻopihapiha.

2) maʻi o Alzheimer

ʻO ka hoʻonuiʻana i kāuʻaiʻai o kaʻaina ke pale aku i ka maʻi o Alzheimer, e like me ka aʻoʻana o 2004 mai ka Journal of Neurology, Neurosurgery, a me ka Psychiatry .

ʻIke i nā makahikiʻeono o kaʻikepiliʻai a me nā hōʻike loiloi o 3,718 mau mākua, uaʻike nā mea kākau o kaʻimi i keʻano o kaʻaia ke paleʻana i ka uluʻana o ka maʻi o Alzheimer. Eia kekahi, ua pili ka meaʻaiʻoi aku o kaʻaina me ka māmā haʻahaʻa o ka emiʻana o kaʻike.

3) Diabet

Ua hōʻikeʻia he mauʻano noiʻi he hiki i nā kānaka ke loaʻa i ka maʻi dia. I loko o kahi noiʻi 2000 mai ka Journal of the American Medical Association , no ka mea, uaʻike nā kānaka noiʻi ua kōkuaʻo niacin i ka paleʻana i nā haʻahaʻa o HDL cholesterol e pili pinepine i ka maʻi hē. ʻOiai uaʻikeʻia ka haʻawina i loaʻa i ka lolocin i ka piʻi haʻahaʻa o ka nui o ke koko koko,'ōlelo ka poʻe kākau e "hiki ke mālama ponoʻiaʻo niacin i nā maʻi me ka maʻi diabetes."

NāʻAla'ē aʻe

ʻOiaiʻo nā noiʻi mua e hōʻikeʻia ai e hiki i ka lolokin ke kōkua i ka hoʻemiʻia o kaʻeha i loko o nā kānaka me ka osteoarthritis a me ke kōkua ma ka mālamaʻana i nā palapala kākau, pono e mālamaʻia nā haʻawina hou i mua o ka hikiʻana i ka lolocin no kēlā me kēiaʻano.

Nā kumuhana

Loaʻaʻo Niacin i loko o nā meaʻai he nui, e like me:

nā huahana laʻau
nā hua
ka iʻa
nā lean
nā lemu
nā hua
ka mea hānai

Eia hou, hiki ke loaʻaʻo niacin i loko o nā meaʻai momona a me nāʻai.

Kāpena

ʻOiai e palekana ana ka lolokin no ka hapanui o nā kānaka, hiki i ka NIH ke mālama i nā hopena o ka hopena (e like me ka puhiʻana, keʻokiʻana, kaʻiliʻana, a me ka poniʻana i kaʻili).

I kekahi mau kumu, hiki i ka lolokin ke hoʻonāukiuki i ka maʻi'ōpū, ka huhū o ka'ōpū, ke kauwela, a me ke kinoea.

Hoʻopāʻia, he mea hōʻino paha ia i nā kānaka me kekahi mau ola olakino (e like me nā maʻi o ka'ōpū, nā maʻi kīkiʻi, nā maʻi o ka gallbladder, a me nā maʻi ulia) a me nā kānaka e lawe nei i nā lāʻau (e like me nā kahe o ke koko, nā hōʻailona diabetes, a me nā statins).

Hiki iāʻoe ke loaʻa i nā'ōlelo hou aʻe no ka hoʻohanaʻana i nā hoʻopaneʻi maʻaneʻi.

Ke hāʻawi nei i kēia mau mea pilikino, he mea nui eʻimi i ke aʻo aʻo kino inā e noʻonoʻoʻoe i ka hoʻohanaʻana i nā mea pani.

Kahi e Loaa ai iā lākou

Loaʻa i nā mea kūʻai maʻamau ma ke kelepona, loaʻa nui nā supplements o niacin i ka hapanui o nā mea kūʻai lāʻau kūʻai, nā mea kūʻai kūʻai, a me nā hale kūʻai kūʻai i nā meaʻai.

Ke hoʻohana nei ia mea no ke ola

Ināʻoe e noʻonoʻo ana i ka hoʻohanaʻana i ka'ōlelo,'ōlelo mua i kāu kauka. E hoʻomanaʻo i keʻano o ka lāʻau lapaʻau e ponoʻole e hoʻohanaʻia e pani ai no ka mālama maʻamau. ʻO ke ola pono'īʻana i kahi kūlana a palekana a hōʻole paha i ke kūlana maʻamau i nā hopena maikaʻi paha.

> Kālā:

_{NĀ HAUMĀKAI HALAU,ʻO Boden WE, Probstfield JL, Anderson T, Chaitman BR, Desvignes-Nickens P, Koprowicz K, McBride R, Teo K, Weintraub W. "Niacin ma nā maʻi me nā haʻawina cholesterol haʻahaʻa HDL e loaʻa ana i keʻano o keʻano o ka lāʻau."} _{N Engl J Med.} _{2011 Dec 15; 365 (24): 2255-67.}

_{ʻO Brown BG, Zhao XQ, Chait A, Fisher LD, Cheung MC, Morse JS, Dowdy AA, Marino EK, Bolson EL, Alaupovic P, Frohlich J, Albers JJ.} _{"Simvastatin a me nāʻaia, huaʻai antioxidant, aiʻole nā hui pūʻia no ka paleʻana i ka maʻi maʻi."} _{N Engl J Med.} _{2001 Nov 29; 345 (22): 1583-92.}

_{Elam MB, Hunninghake DB, Kalikimaka KB, Garg R, Johnson C, Egan D, Kostis JB, Sheps DS, Brinton EA.} _{"Ka hopena o ka niacin ma luna o ka lipid a me ka lipoprotein mau kiʻekiʻe a me ka lāʻau glycemic i nā poʻe maʻi me ka maʻi diabetes a me keʻano āpau:ʻo ke ADMIT study: He ho'āʻo kūkaʻina.} _{ʻO JAMA.} _{2000 Sep 13; 284 (10): 1263-70.}

_{Ganji SH, Kamanna VS, Kashyap ML.} _{"Niacin a me cholesterol: i loko o ka maʻi o ka maʻi o ka maʻi (cardiovascular)."} _{J Nutr Biochem.} _{2003 Jun; 14 (6): 298-305.}

_{ʻO Guyton JR, Fazio S, Adewale AJ, Jensen E, Tomassini JE, Shah A, Tershakovec AM.} _{"Ka hopena o ka maʻi hoʻomau o ke diabolo hou i waena o nā maʻi o nā maʻi hyperlipidic i mālamaʻia me ka ezetimibe / simvastatin ma kahi ho'āʻo o ka hoʻomaluʻana."} _{Ka mālama maʻi diabetes.} _{2012 Apr 35 (4): 857-60.}

_{Honolulu HI, Kahului HI, Kailua Kona, HI Hanalei, HI Kapolei, HI Kapolei, HI.} _{"Nā hopena e pili ana o ka lovastatin a me ka niacin ma ke hypercholesterolemia mua.} _{Hoʻopaʻa i ka Mokuna Med.} _{1994 Jul 25; 154 (14): 1586-95.}

_{Meyers CD, Kamanna VS, Kashyap ML.} _{"Niacin kelepa ma atherosclerosis."} _{ʻOlelo Curr Lipidol.} _{2004 Dec, 15 (6): 659-65.}

_{Nā Papa Hoʻonaʻauao o Nā Aupuni.} _{"Niacin a me niacinamide (Vitamin B3): MedlinePlus Hoʻohui."} _{ʻApelila 2011.}

_{ʻO Morris MC, Evans DA, Bienias JL, Scherr PA, Tangney CC, Hebert LE, Bennett DA, Wilson RS, Aggarwal N. "Dietary niacin a me ke kumu o ka maʻi o Alzheimer a me ka emiʻana o ka manaʻo."} _{ʻO J Neurol Neurosurg Kekikipi.} _{2004 Aug; 75 (8): 1093-9.}

Ka Hoʻohaha:ʻO kaʻike ma kēia pūnaewele kahi i hoʻolālāʻia no nā hoʻonaʻauao wale nō aʻaʻole ia he pani no ka'ōlelo aʻo, diagnostics or treatment by a physician licensed. ʻAʻole i manaʻoʻia e uhi i nā mea palekana a pau, nā hana maʻamau, nā kūlana a iʻole nā hopena pilikia. Ponoʻoe eʻimi i keʻano o ka hoʻoponopono kūikawā no nā nīnau pili olakino a nīnau i kāu kauka ma mua o ka hoʻohanaʻana i ka lāʻau lapaʻau'ē aʻe a iʻole e hoʻololi i kāu kaulike.